Gene Expression Profiling of Cutaneous Injured and Non-Injured Nociceptors in SNI Animal Model of Neuropathic Pain

Upregulation of the voltage-gated sodium channel beta2 subunit in neuropathic pain models: characterization of expression in injured and non-injured primary sensory neurons.

The development of abnormal primary sensory neuron excitability and neuropathic pain symptoms after peripheral nerve injury is associated with altered expression of voltage-gated sodium channels (VGSCs) and a modification of sodium currents. To investigate whether the beta2 subunit of VGSCs participates in the generation of neuropathic pain, we used the spared nerve injury (SNI) model in rats t...

Sodium Hydrosulfide Relieves Neuropathic Pain in Chronic Constriction Injured Rats

Aberrant neuronal activity in injured peripheral nerves is believed to be an important factor in the development of neuropathic pain (NPP). Channel protein pCREB of that activity has been shown to mitigate the onset of associated molecular events in the nervous system, and sodium hydrosulfide (NaHS) could inhibit the expression of pCREB. However, whether NaHS could relieve the pain, it needs fu...

Comparison of organizational commitment, job stress and personality traits among injured and non-injured employees of Isfahan refinery

Background: In recent decades, scientific growth has led to industrial progress and increased welfare for humans. But there are other unintended consequences, including work-related accidents. The incidence of occupational accidents in the various countries of the world, especially in the industrial sector, is increasing over time. So that occupational accidents are one of the most important pr...

Electrophysiological Markers for Neuropathic Pain in Spinal Cord Injured Subjects

comparative study of pain relieving effect of dry cotton pellet and eugenol cotton pellet in the reduction of pain in emergoney pulpotomy

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